Abstract
The excellent antithrombogenicity of small caliber vascular graft can be obtained by the prompt and complete neoendothelialization of the luminal graft, determined by the graft fabrication, the inner structure of a graft wall, the speed and amount of perigraft tissue ingrowth. In addition, the graft should have elastic properties to prevent a mismatch between the mechanical properties of a vascular graft and its host artery, which can cause eventual thrombosis and graft failure. Since our heparin slow release collagen graft has such properties as mentioned above, its clinical application can be possible if the problem of antigen-antibody reaction is solved.