EVALUATION OF POLYPROPYLENE MEMBRANE WITH WATER-SOLUBLE CHAIN FOR PLASMA SEPARATION

Abstract

A hydrophobic polypropylene (PP) membrane was modified to a hydrophilic one having water-soluble chain on its surface by means of non-equiliblium plasma initiating graft copolymerization technique using N, N-dimethylacrylamide (DMAA) as monomer. Plasma filtration flux of pDMAA-graf ted PP (PP-g-pDMAA ) membrane was almost equal to that of PP one without grafting. PP-g-pDMAA membrane showed little increase in complement and excellent blood compatibility caused by the water-soluble pDMAA chains which effectively suppress adsorption and denaturation of blood elements.