Abstract
Renal function on extracoporeal circuration (ECC) was evaluated by urinary microalubumin (U-Alb) that was seen to be reflected early renal glomerular damage, on 21 patients who were undergone open heart surgery. Changes of U-Alb and AlbI (u-AlbI/U-Cr) were evaluated. The patients were divided into two groups, according to AlbI levels. U-Alb levels decreased during ECC and increased after operation, then decreased gradually. AlbI increased remarkably during and after ECC, and after operation. The effects of factors concering to operation and ECC on U-Alb excretions were evaluated, but there were no relationships with them. The cases that kept AlbI above mean levels to 12 hours after operation, also had indicated AlbI above mean level before operation, and of ten complicated Diabetis Melitis. Increase of U-Alb excretion during ECC thought to be mainly due to functional damage of renal glomeruli, but the cases that already have had renal dysfunction before ECC should be taken care of after operative management, because organic change might be taken after ECC.
