Abstract
It cannot be redused to contact the blood with gas and the biomaterial. And then, complement is activated and appears anaphylatoxin. We compared PHO to HF-4000, SILOX, CAPIOX II on peripheral blood leucocyte counts, immunoglobuln and complements. The coparison of the corrected values showed that SHO had less loss of those protein factories than any other membronous oxygenator. It dued to membronous biomaterial, silicone. There were no differences between extra and intra capillary corporeal circuration. PHO, which we developed was more less than SHO. But, it was not inferior to HF-4000, CAPIOX II.