CLINICAL STUDIES OF EXTRACAPILLARY BLOOD FLOW TYPE HOLLOW FIBER MEMBRANE OXYGENATOR, CAPIOX E, IN COMPARISON WITH BUBBLE OXYGENATOR DIDECO D700

Abstract

CAPIOX E membrane oxygenator (Group-C) consists of extracapillary blood flow and gravity drainage. We used CAPIOX E for open heart surgery in 30 adult patients, and the results were compared with bubble oxygenator DIDECO D700 (Group-D), used in 8 patients. The following results were obtained. (1) Plasma free hemoglobin was same in the two groups. (2) Group-C demonstrated higher platelet counts (p<0.05), and better preservation of aggregation mechanisms (p<0.01). (3) Factor VIII was also less reduced in Group-C, however, Fibrinogen, Factor X, and XII were much higher in Group-D. This study indicates that CAPIOX E is superior to DIDECO D700 as regards to hematocoagulation activities during bypass.