Abstract
For continuous monitoring of changes in plasma free hemoglobin (Hb) concentration during extracorporeal circulation, a prototype system of compact hemolysis sensor was developed. Blood-plasma was continuously separated from blood by a disk filter type plasma separator installed on a housing wall of a non-positive displacement type blood pump. Hb concentration change was detected as absorbance change of plasma by an optical monitor unit consisted of LED (λmax=560nm), interference filter (λ=540nm) and photodiode. The Hb concentration values measured by this system were compared with those by conventional colorimetric method, and close agreement between the simultaneous data from these two methods were observed.
