EFFECTS OF SYNCHRONOUS SYSTOLIC DRIVING OF LVAD IN COMBINATION WITH IABP ON CARDIAC PERFORMANCE IN CANINE HEARTS

Abstract

Three different ECG synchronous driving modes of LVAD were performed in nine anesthetized dogs: diastolic driving mode (D), systolic driving mode (S), systolic driving mode in combination with IABP (SI). In both S and SI, the assist flow was significantly higher and the stroke work was significantly lower than those in D. The aortic pressure at the beginning of left ventricular (LV) ejection (APej) was higher in the order of D, S, and SI. The peak LV pressure was significantly lower in SI than those in S and D. The LCX flow in SI was similar to that in D. We concluded that synchronous systolic driving of LVAD became more effective by combination with IABP in terms of systolic unloading and diastolic augmentation.