Abstract
Dalysate with acetate Na (D-A·Na) was changed to that with bicarbonate Na (D-B·Na) in 25 hemodialysis (HD) patients. Subjective symptoms were improved in eight out of 25 cases. There was no particular change in 13 cases. Subjective symptoms were worsened in four cases. Progress of anemia was observed in two out of the four cases. Anemia in one of the two was improved after changing from D-B·Na to D-A·Na. Hypertension was observed before HD therapyand was improved by HD therapy with D-A·Na in 11 out of 25 petients. Hypertension was relapsed in 6 out of 11 cases after changing from D-A·Na to D-B·Na. Acetate Na is thought tobe an anti-hypertensive drug for some HD patients with hypertension, because it has pharmachological action to dilate peripheral blood vessels.