THE DEVELOPMENT OF INTRAVENOUS CATHETER WITH PERCUTANEOUS DEVICE MADE OF SINTERED HYDROXYAPATITE

Abstract

For a long-term parenteral nutrition, catheter-related sepsis must be controlled. For this purpose, we developed a intravenous catheter with percutaneous device made of dense sintered hydroxyapatite (HAp-PD), and tried to use it for 2 patients. No disinfection treatment was made since 30 days after implantation. HAp-PD were removed after 60 and 96 days after implantation, without no infectious symptoms clinically. Histologically, skin attached to HAp-PD closely and little inframmatory change was seen. This study proved excellent biocompatibility and clinical usefullness ofHAp-PD.