Abstract
The bullet type glucose sensor and the needle type glucose sensor have been developed for an artificial pancreas. There are some problems on working of glucose sensor after implantation. The glucose sensor did not work especially under low oxygen concentration for a long time. We tried to work out these problems and tried to change semipermeable membrane. We found out that glucose semipermeable membrane was changeable. We reached to the conclusion that the semipermeable membrane should be developed for a long-lived glucose sensor.