Abstract
Highly permeable (HP) membranes have higher solute permeabilities than conventional ones. As a result, the contribution of dialysate film mass transfer resistance increased on HP dialyzers. It should be reduced to improve the mass transfer performance of HP dialyzers. Little is known concerning the technical design of dialyzers, considering dialysate film mass transfer resistance. This paper describes the technical design of dialyzers to reduce the dialysate film mass transfer resistance. The dialysate film mass transfer coefficient increased with the fiber density. The increase in fiber density increased the mass transfer rate of HP dialyzers more effectively than that of conventional dialyzers. Keller's equation, commonly used for the technical design of dialyzers, should be modified because the dialysate film mass transfer coefficient calculated from the equation did not agree with those determined by a dialysis experiment.
