EXPERIMENATAL ANALYSIS OF BIVENTRICULAR BYPAS—HEMODYNAMIC AND HORMONAL STUDY

Abstract

Hemodynamic and hormonal changes were studied in 11 sheep with electrically fibrillated heart. Their circulation was maintained by the biventricular bypass with pneumatic driven pusher-plate pumps. Periods of survival ranged from 2 to 48 days with average of 11.3 days. Hemodynamic parameters except for central venous pressure (CVP) were kept physiological range, and CVP slightly elevated to 10-13mmHg. Adrenaline did not change significantly. Serum levels of triiodothyronine and thyroxine decreased significantly, and did not return to control level. Atrial natriuretic polypeptides increased significantly 4 days after the mild CVP elevation. In conclusion, biventricular bypass in the animal with ventricular fibrillated heart altered hormonal situation while hemodynamic parameters were maintained within almost normal range.