Abstract
motion of CarboMedics aortic prosthetic heart valve. To investigate the relationship between the asynchronous motion of the bi-leaflet prosthetic valve and its function after implantation, in vitro and in vivo study of the CarboMedics aortic prosthetic valve was carried out.In vivo study: Asynchronous motion of the aortic CM valves was analyzed quantitatively using X-ray cinefilms (7 patients). To calculate open angle as a function of time we have developed the computerized image processing system. Asynchronous motion were seen during peak and deceleration period of systole in all 7k cases. Average differences of open angle between the leaflets were 5.7 degree (std. 1.5 degree, range between 4.0-7.9 degree). Although all cases showed asynchronouss motion, there was no episode of valve dysfunction such as hemolysis. In vitro study: Mock circulatory system with high speed motion monitoring was built and motion of the CM valve were measured. As a results, asynchronous motion was seen at acceleration and deceleration phase of systole. No asynchronous motion at peak of systole showed the limitation of in vitro study. Hemodynamic study linked with in vivo valve motion analysis is promising to make a rational explanation on clinical phenomenon such as hemolysis and mechanical failure.
