Abstract
Arterial blood ketone body (AKBR) was measured in 32 patients performed cardiopulmonary bypass (CPB). AKBR levels decreased significantly at 5 minutes after the start of CPB compared to before CPB. During CPB it remained low level and then recovered 24hrs after CPB. However, in two patients with thoracic aneurysm using F-F bypass, AKBR showed normal levels during and after CPB. Initial drop of blood pressure in F-F bypass was less than that in standard CPB. The aforementioned changes in AKBR level were assumed to be significantly affected by its initial drop of blood pressure in early phase of CPB. In experimental study with the dog, KBR values were mainly affected by portal flow rather than blood pressure.
