Abstract
A rotor type liquid-liquid artificial oxygenator was deviced. This oxyge-nator was comprised of a cylinder and 18 rotors connecting together by axis. Oxy-genated perfluorocarbon (perfluorooctylbromide) streamed in the lower part of the oxygenator and added oxygen to venous blood flowing upon the layer of perfluoro-carbon since the gravity of perfluorocarbon was heavier than that of blood. In addition, the rotors were rotated in the oxygenator and mixed with blood and per-fluorocarbon. Animal experiment using 3 mongrel dogs was undergone and oxygen exchanging capacity was appliciated. Oxygen intake capacity of this oxygenator was sufficient (Qp/Qt=0.48-0.83) and carbon dioxide discharge was efficient ( CO2/PaCO2 =0.05-0.10) under the condition changing blood and perfluorocarbon flow rate from 104ml to 300ml during 2 hours. Pathological examination after 2 hour perfusion showed no deposition of perfluorocarbon in the capillaries of lung and liver.
