Abstract
A cord is utilized as it is. The umbilical cord vessels have been tested in forms of raw (RM), alcohol (AL)- or glutaraldehyde (GA)-treated materials. AL and GA are equally superior to RM on pressure tolerance test. Tensile strength test showed that AL and GA both mechanically reenforced. The mechanical property is stable and irreversible in GA. Amino acids analysis indicates that crosslinking in GA takes place mostly among the lysine residue. Further assessment of material in view of surface characterization, antithrombogenicity and immunology are underway.
Based on these studies, 23 implants have been carried out clinically, No severe complication have thus far been encountered with the longest patency of 2 years.
The studies have indicated feasibility of the material for the purpose.
