Jinko Zoki
Online ISSN : 1883-6097
Print ISSN : 0300-0818
ISSN-L : 0300-0818
The study on the necessary equipment to eliminate ammonia in treating for malignant tumor by L-asparaginase.
A. YAMADAN. KABEIM. KIKUCHIE. MACHIYAMAY. SAKURAIK. KIHARAK. ITO
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JOURNAL FREE ACCESS

1978 Volume 7 Issue 1 Pages 112-115

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Abstract
High ammonia concentration of blood was seen ingiving L-asparaginase and L-arginine. So that the necessary equipment to eliminate ammonia was needed. On account of high rapid elimination of ammonia electro-dialyser was used. The menbranes of CMV and AMV as electrodialyser were used and electrified between them. Electro-dialyser to use ultrafiltration has high point of rimiting current density. So that the effects on electro-dialyser were quantitatively analysed in vivo experiments. With increasing electrical current, the rapidity and efficiency of blood ammonia removal was increased. With maintaing acid base equilibrium, electrolyte (Na, K and ci) and osmotic pressure, ammonia was eliminated rapidly.
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© The Japanese Society for Artificial Organs
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