Abstract
Non-protein N substances such as urea and ammonia are converted to amino acid and protein in the rumen of ruminant by virtue of microorganisms. Considering the possible application in hepatic and uremic patients, converting activity of micrococcus glutamicus of urea and ammonia to L-glutamate was examined. Fresh, lyophilized or sonicated micrococcus glutamicus reduced urea concentration and produced L-glutamate in the medium. Oral or ex vivo application of the treated. microorganism is suggested to be useful after sophistication of methodology in hepatic and uremic patients.
