According to our total artificial heart experiment, the long survival can be achieved by maintainig of cardiac output in normal rate, which is 80 to 100ml/kg.
When an experimental animal is made exercise, its cardiac output should be increase. The amount of increased cardiac output is seemed to relate venous pressure, peripheral resistance or partial O2 pressure of blood. The relation between load of exercise and such physiological data, as CVP, TPR and O2 consumption, were analysed quantitatively in this report.
The results were; 1) By CVP, the cardiac output of artificial goat during exercise could not be determined. 2) TPR has some relation to the cardiac output but we need more precise study. 3) O2 consumtion is seem to be most useful information to control total artificial heart.
