Polyvinylalcohol (PVA) was used for microencapsulation of beaded activated charcoal. Encapsulated charcoal was immersed in heparin solution to provide the capsule with anticoagulability. PVA proved to be a suitable material for microcapsulation. The capsule was found smooth by scanning electron microscope and did not reduce adsorptive capability of the activated charcoal, however effects of heparin incorporation could not be manifested by in vitro study using human blood as well as in extracorporial circulation using dogs.
