抄録
We have developed an automatic UF control system which makes it possible to regulate UFR easily and to pre-set the total OF precisely. This system consists of a chamber divided into two parts by a flexible silicon diaphragm, a dialyzer and a negative pump. They make up the closed circuit, accordingly, a amount of fresh dialsyate drawn from one side of a chamber should be equal to that of used dialysate filled the other side up from the dialyzer. Then, the fluid extracted from this closed circuit by the UF metering pump will be replenished from the blood compartment of the dialyzer. Combination of two chmbers which operate alternately, one being at dialysis position while the other is at dialysate renewal position, makes continious dialysis possible. Clinically more than 150 dialysis treatments have been tried with this apparatus in combination with 11 different types of dialyzers. This system was independendent from venous pressure and blood flow rate changes. The discrepancy between pre-set total UF and patient weight loss was within the measuring limits. Its standard deviation was 0.15 Kg..