抄録
Total heart-lung bypass wit h closed circuit was performed under automatically controlled CVP, and oxygen consumption and fraction rate of SVC and IVC return were studied in our previous report.
In this report histological changes of the liver, portal vein pressure, cerebral drainage and total systemic peripheral resistance during heartlung bypass were discussed in variously controlled CVP. Consequently, during our closed circuit heart-lung bypass, 7-9 cmH2O CVP was recommended to minimize histological and metabolic changes and to keep venous return stable.