抄録
Direct hemoperfusion with albumin coated, bead shaped, micro-encapsulated, activated charcoal and hollow fiber kidney were performed so times on is patients of hapatic coma.
survival of 3 patiens and improvement of consciousness in 7 patients were observed. In autopsy, the liver histology of almost cases without any clinical effect for direct hemoperfusion showed massive necrosis.
after 3 hours direct hemoper fus ion, elevated plasma amino acid level were lowered and some kinds of plasma amino acid, especially Threonine and Methionine were remarkably decreased.
However, remarkable change in chemical data of liver function was not observed.
