Experimental studies on the transvenous closure of the patent ductus arteriosus using a newly developed catheter system

Abstract

A newly developed catheter system, which aims to the transvenous closure of the patent ductus arteriosus (PDA) without thoracotcmy, is reported. This catheter system consists of universal hock, Ivalon sponge plug, ratchet bar and ratchet mechanism.
First of all, the universal hock anchors in the descending aorta at the orifice of PDA through the venously introduced catheter. The ivalon sponge which is plugging in PDA is then fixed by the ratchet mechanism. A smooth function of the designed mechanisms and a successful closure of the PDA are demonstrated both in the fundamental studies using the PDA model circuit and in the animal experiments using dogs constructed PDA.
The presented catheter system could possibly be used clinically after the meticulous chronic experimental studies.