熱交換器内蔵膜型人工肺の開発

抄録

We have succeeded in developing a new disposable membrane oxygenator with a built-in heat exchanger, which consists of layers of a tubular silicone rubber membrane with an inserted blood side mesh spacer and a gas side mesh envelope.
This device with 1.6m² surface area (pediatric size) has an oxygen transfer of 94ml/min/m² and a carbon dioxide transfer of over 50ml/min/m² at a blood flow rate of 2.5l/min, and also has good heat exchange characteristics.
The good results of total cardiopulmonary bypass experiments (durating up to 4.5 hours) show that our new device is efficient for clinical use.