人工臓器
Online ISSN : 1883-6097
Print ISSN : 0300-0818
ISSN-L : 0300-0818
悪性腫瘍の治療時(L-asparaginase使用)に生ずるアンモニア除去装置に関する研究
山田 明夫町山 悦子壁井 信之菊地 真桜井 靖久木原 一彦伊藤 光一伊藤 陽一郎
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1979 年 8 巻 1 号 p. 101-104

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High ammonia concentration of blood was seen on giving L-asparaginase and L-arginine. So that the necessary equipment to eliminate ammonia was needed. On account of high rapid elimination of ammonia electro-dialyser was used in the report of this meeting of last year.
However electro-dialyser has complicated operation and problem of the amount used of blood. So orelite as adsorptive substance in the study of this time was used. As the result of that, ammonia was eliminated rapidly like electro-dialyser, L-argine was hydrolyzed and aspartic acid increased.
Acid base equilibrium, electrolyte of serum (Na, K and cl) and osmotic pressure were maintained.

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