The majority of currently available material test might have a definite limitation in evaluating the true antithrombogenicity of test materials, because in these preparation, the continuous contact of inserted test material with the inner surface may initiate early thrombus formation on the transitional area between the test material and the intima of cardiovascular bed.
Therefore, we developed new in vivo material test - atnial floating ring test - to evaluate real antithrombogenicity of test material itself. In our newly deviced test, the test material ring was introduced into the canine atrium which was stayed floating inside without continuous contact to the atrial wall.
The test material Silastic 3140 RTV was assayed using our atrial floating ring test, and the result was that by our atrial floating ring test, this material has higher antthrombogenicity than that obtain from vena cava ring test previously done in our laboratory.
In conclusion, our atrial floating ring test was thought to be superior to the currently available material test.
