This report represented the clinical cases who were used the medical materials immobilized urokinase in surgical therapy and operation.
It has been demonstrated by our experiments that these materials had the antithrombotic action in vitro and in vivo. Disinfection was carried out in the method of ethyleneoxide gas or gamma rays.
The clinical cases were mentioned below:
1. patients who underwent the intravascular hyperalimentation (10 cases): nylon tube or perplene tube which is inserted into caval vein is prepared by urokinase to link it on the surface.
2. patients who underwent the vascular operation (9 cases): nylon suture material which sews the vessel wall is prepared by urokinase.
3. patients who underwent the Handley's method for drainage in lymphedema: dacron thread or nylon thread which is implanted into subcutaneous tissue is prepared by urokinase.
At present, we have had the good results, as shown in Figure 3, 5 and 7.
