D52 高分子材料によるイヌにおける長期埋植時の組織反応

抄録

Twenty three polymeric materials were implanted siibcutaneously in dogs for 26 or 36 months. Tissue response induced by various polymeric materials was mostly correlated with the elution of leachables from materials and degradation of polymers. Chronic inflammatory reaction was noted in 4 cases. In most cases the materials were surrounded by the thin fibrous tissue capsules (less than 0.15mm) in which there was some difference in cellularity among the materials. We proposed a picture of tissue response which will be desirable for implant materials.