Four types of Nylon, 3 polybutylene terephthalates, 5 polypropylenes, 4 segmented polyesters, 3 polyolefinic thermoplastic elastomers and polyacetal copolymer were tested and compared with medical grade Silastic and Tygon by repeated extraction test, hemolysis test and tissue culture test. Cell morphology was also studied by scanning electron microscopy in tissue culture test. Eight of 20 materials tested seemed to be less suited for biomedical material. The materials based on polybutylene terephthalate and polypropylene gave the promising results as a potential biomedical material.