Abstract
Collagen-spun fibers were buried in the tissues of various organs (e. g., esophagus, lung, heart, aorta, stomach, intestine, liver, kidney, pancreas, urinary bladder, uterus, and tendon) of dogs in order to clarify whether they were available as materials for artificial organs. They were examined for reaction and absorption in the tissues at given intervals.
As a result, these fibers were absorbed and induced a bioreaction in such manner as specific to the respective organ and to the site of implantation.
It was concluded that collagen-spun fibers caused only a mild reaction as foreign matter at the site of implantation and had a high affinity to every organ and tissue.
