Three kinds of new techniques for purification of blood were investigated. Combination therapy of dialysis and direct hemoperfusion in series was applied to refractory uremic neuropathy which had not been improved with increase of squaremeter -hour and frequency per week. H emofiltration by post dilution technique was applied to patients whose hypertension, hypotension. hyperlipidemia and/or hyperphosphotemia had not been improved with standard dialysis. Continuous ambulatory peritoneal dialysis(C. A. P. U) was tried in one case. Combination therapy of dialysis and direct hemoperfus ion showed remarkable improvemment in three cases, in patients' own complain and MNCV. In hemof iltation group, disappearance of disequilibrinm syndrome was only one identified symptom so far as the present study was concerned. There were no significant differences between dialysis and hemofiltration in hypertension, hypotension and hyperlipidemia. C. A. P. D. proved to be one of the reliable tools for treatment of uremia.
