人工臓器
Online ISSN : 1883-6097
Print ISSN : 0300-0818
ISSN-L : 0300-0818
透析における循環動態
とくに心拍出量について
垣内 孟青木 正馬渕 非砂夫村尾 之義田端 義久岸 泰三中橋 弥光伊地知 浜夫
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1979 年 8 巻 4 号 p. 440-445

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C. O. changes between overhydration group and good-controlled one by water balance before, during and after hemodialysis were evaluated in this study.
During it they were grossly classified into two different C. O. patterns. Overhydration group showed type A C. O. pattern (Y=aX2+bX+c, a<0, b>0) and good-controlled, type B C. O. pattern (Y=aX+b, a<0).
In comparison with C. O. changes at predialysis and postdialysis that we measured 10 minutes after completion of return of coiled blood, between two groups, three different subgroups such as increased, non-changed and decreased at postdialysis, were present respectively. Hence, imaginary considerations based on only comparative data between predialysis and postdialysis may be impossible to explain intradialytic hemodynamics because of progressing remarkable hemodynamic changes during it.
Intradialytic disequilibrium syndrome such as nausea, vomiting, jawning, general lassitude or abdominal discomfort started to appear at level of C. O. reduction of 1.5-2.0l/min from initial C. O. Several cases of shock were experienced and their C. O. values, then, were less than 3.0l/min. By rapid infusion with approximately 200ml of 5% D/W, however, C. O. was increased markedly and instantaneously, and it is generally sufficient to be recovered from shock-state as well as intradialytic disequilibrium syndrome. Judging from these facts it might be possibly true that hemodynamic changes, at least, are contributory directly and indirectly to the appearance of this syndrome.
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