The non-buffer dialysis is a method the authors have newly taken up this time using a dialysate containing neither acetate nor bicarbonate in the solution. That is, to supplement Na+ and HCO3- in short, 7w/v % of NaHCO3 is given with a microsyringe continuously into blood from the venous siee, thus availability has been tested in vitro and in vivo. The test in vitro revealed that to make Na value in arterial blood from 142 (pre) to 134 (post mEq/l, it arrived at an ideal stage with 2.4-4.2ml/min. Meanwhile, in vivo, using dogs at HD of 3 hours to raise Na value of 141 (pre) to 135 (post) mEq/l and HCO3 value of 15 (pre) to 22 (post) mEq/l, satisfactory values were obtained with 1.8-2.7ml/min, in use of synchronized pH monitor. From these test results it can be considered that when NaHCO3 is injected appropriately, there should not be any danger of causing problems.
