Abstract
Three kinds of expanded polyietrafluoroethylene (EPTFE) grafts (10, 20 and 30μ fibril length) 5cm in length with 7 to 10mm diameters were implanted in the infrarenal venae cava in 43 dogs with and without administration of a 20mg/kg of dipyridamole daily for one month after implantation. In the non-dipyridamole group, the over all potency rate in the early (less two weeks) was 65.0%, but, in the late (two weeks to 10month) was reduced to 40.0%. In the dipyridamole group, the over all patency rate in the early was 78.3%, but, in the late was reduced to 52.2%. The 10μ fibril length group with and without dipyridamole had the high patency rate of 85.7% in the early campared with the 20μ & 30μ groups, but, the over all late patency in the these three groups was all poor.
It appears that a 10μ fibril length EPTFE groft may be superior to other materials for inferior versa cave, replacement with the administration of dipyridamole. However, additional studies shoud be necessary to obtain tree better long term patency.
