抄録
The feasibility and safety of selective kidney cooling using a three-lumen, two-balloon catheter were studied. The catheter was originally developed for selective venography (renal venography, hepatic venography), blood sampling and organ irrigation. The shaft part of catheter was made of silicon rubber and the balloon part was made of latex rubber. The diameters of the catheters used in the present experiment are 10F, 12F and 16F. The intervals between the two balloons are 7cm and 10cm. In 15nongrel dogs with their BW ranging from 7 to 15Kg, the catheter was introduced through the femoral or iliac artery and advanced into the abdominal aorta near the orifices of the renal arteries so that the proximal and distal balloons were located distally and proximally to the orifices, respectively. The location of the catheter in relation to the renal arteries was confirmed rentogenographically by injecting 10 to 15ml of 76% Urografin. After respiratory arrest by administration of succinylcholine the irrigation was started. The greater the irrigation speed per minute was, and with the shorter distance between the balloons, the higher was the cooling rate of the kidney surface. The pressure elevation between the balloons monitored by another catheter was in proportion to the irrigation speed.
