抄録
Many kinds of polymer, as cellulose acetate, polycarbonate and polyvinylalcohol, have not been satisfied on clinical use complitely.
We developed a new plasma sepalator using polysulfon hollow fiber and evaluted in vitro and in vivo experiment.
The structure of this membrane have three layer (inside and outside layer: skin layer, midle layer: pound layer).
In vitro examination evidenced that UFR was 1.1-1.6 1/mmHg.hr.m2.
In vivo examination, we carried plasma exchange for hepatic failure in dogs.
As the result of plasma exchange at polysulfone, serum LDH, GOT and levels were decreased in clearly.
Polysulfon membrane will be hoped as a plasma separator and other application of a line from the view point of its flexible structure.
