抄録
We developed a new type of bead activated charcoal (PAC). In the previous report, we demonstrated that PAC can be used for direct hemoperfusion without encapsulation. This time, the clearances of creatinine, uric acid and vitamin B12, carbon powder relaese and compatibility fo blood cells were studied, comparing with four kinds of encapsulated charcoals (CAC).
The clearances of three substances of PAC were superior to the cellulose coated AC, and same to the poly-MAMA coated AC. The degree of carbon powder release was less and damages of blood cells were same compared with CACS.
In conclusion, PAC can be used in noncoated state safely for direct hemoperfusion and has advantages to release minimal carbor powders and to save the procedure of encapsulation.
