抄録
24 cases of acute hepatic failure and 6 cases of uremic neuropathy were treated with direct hemoperfusion.
only 4 cases of hepatic failure survived, but levels of conciousness and EEG finding were improved with DHP therapy. In majorty cases whose clinal symptomes improved with DHP, initial conciousness level were in stupor and background activities were in the range of θ-δ band, however fatal cases were in the δ band.
DHP accompany with hemodialysis showed obvious improvement in 4 cases of uremic neuropathy. In 2 cases neurological improvement appeared in eary month therapy with DHP, and nerve biopsy revealed no degenerative changes.
From these findings it is suggested that hepatic coma and uremic neuropathy with only functional change are indicated for DHP therapy.