Journal of Advanced Science
Online ISSN : 1881-3917
Print ISSN : 0915-5651
ISSN-L : 0915-5651
Paper
シリル基を有するメタクリレート系ポリマーの生体適合性とMg合金への耐食性付与
Akiho KONNOChie YAHATAAkira MOCHIZUKI
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2019 年 31 巻 論文ID: 31104

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Magnesium alloys have recently been expected as a main material for a bioresorbable vascular stent. However, the alloys have a major defect, a very poor corrosion resistance under the wet circumstance such as a body. One of the methods to give the corrosion resistance to the Mg alloys, polymer coating has been investigated. From these back grounds, we designed a new coating polymer, poly(2-methoxyethyl methacrylate¬rantrimethoxysilylplopyl methacrylate), and investigated the effect of silyl group on their biocompatibility and ability to give a corrosion resistance to the alloy. The polymer showed good compatibility with platelets and coagulation system and improved the corrosion resistance in the cell culture medium as a simulated body fluid.
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