Abstract
This report describes the fabrication of microchannels on polytetrafluoroethylene (PTFE) substrates for application to a Micro-Total Analysis System. Some experiments for the replication of linear channels were carried out using a brass mold on which the linear ridges with rectangular cross-section were fabricated. We found an embossing temperature of 250°C, embossing pressure of 14.7 MPa, and holding time of 1 min were optimum for transferring the microstructure to the PTFE substrate. The maximal replication accuracy reached about 95%. Consequently, it was verified that hot embossing is applicable for fabrication of microchannels on PTFE substrates.