From the epidemiological investigation of faeces of human being, multiple resistant Escherichia coli and Citrobacter were isolated. The carrier of Escherichia coli R4 (CM. TC. SM. SA) and R3 (CM. SM. SA) was about 1.4 percent among 1145 healthy human being and was more in patients treated with CM, afflicted with tuberculosis and dysentery among several kinds of in-patients.
Detailed study of the type of multiple resistance of Escherichia coli isolated from 109 tuberculosis patients showed that many kinds of multiple resistance existed and 16 had more than two types of multiple resistance. The multiple resistance of Shigella and Escherichia coli was eliminated after 6 month's storage on cooked meat media.
The contamination rate of multiply resistant Escherichia coli in faeces was described.