The Influences of Coagulase on the Intraperitoneal Infection of Staphylococcus in Mice

Abstract

Clearance of virulent or avirulent Staphylococcus from the peritoneal cavity of mice was inhibited in the presence of coagulase. More abscess were found in peritoneal cavity of infected mice with coagulase than that of control mice without coagulase. Thus, it was suggested that coagulase intensified not only the invasiveness of the organisms but also promoted the abscess formation at the locus of infection.