Abstract
Mechanism of non-specific resistance to the infection with Salmonella enteritidis induced by infection with BCG was studied in CF1 mice and the results obtained are as follows.
1) Clearance foctor to Salmonella enteritidis was not found in the sera from mice vrccinated with BCG.
2) Non-specific resistance could not be transferred to normal mice by injecting with spleen cells and peritoneal cells collected from BCG-infected mice.
3) The non-specific resistance was not reduced by injection of synthetic corticosteroid hormone, “Decadoron”, or by carbon-block, both treaments known to suppress the function of the reticulo-endothelial system.
4) Resistance to Mycobacterium tuberculosis infection could not be induced in mice vaccinated with rough or smooth strain of S. enteritidis.
