CRRT exclusive design of hemofilter excelflo

Abstract

Devices used for continuous renal replacement therapy (CRRT) are required to (1) be usable for a long time, (2) have superior bio (blood) compatibility, and (3) have superior permeability performance and water removal performance. Excelflo has sharp molecular weight fractionation characteristics and high water permeability performance through giving a gradient structure to polysulfone hollow fiber that has superior biocompatibility. In addition, compared with a dialyzer, hollow fibers with a large inside diameter are placed in a low length over diameter (L/D) ratio container to keep down pressure loss and reduce the stimulation of blood cells. Furthermore, in order to realize long-term treatment, we have made improvements such as suppression of blood retention in the header structure and urethane surface as a CRRT-dedicated treatment device. In this paper, we introduce the design concept and features with physical characteristics, etc., and report on the optimal CRRT filter considered by us.