Long-term follow-up and supportive care after pediatric acute blood purification therapy

Abstract

Neonates and children can have a long life after acute blood purification therapy (BPT) and acute kidney injury（AKI）, and it is important to prevent complications to ensure a healthy life. In patients whose renal function declines after acute BPT/AKI, the management of chronic kidney disease is required. In neonates, the detection rate of renal dysfunction early after AKI is low, and follow-up from neonatal to young adulthood is required to detect increases in blood pressure, microalbuminuria, and decreased estimated glomerular filtration rate. In addition, comprehensive growth/development, physical/mental health status, and social adaptation evaluations are required over time and from multiple aspects. When necessary, we provide development support, nursing care, pharmacotherapy, and school and work support. If growth hormone decreases or hypothyroidism occur, treatments such as hormone replacement therapy are provided. After acute BPT/AKI, comprehensive follow-up and supportive care are required with collaboration among specialized pediatric departments. For patients who require long-term intervention, a careful transition to adult care is required.