Rhabdomyolysis and acute kidney injury in a patient with influenza A infection

Abstract

An 87-year-old man was transferred to our hospital because he could not move. He was diagnosed with influenza A infection and admitted to our department. The levels of serum creatinine (Cr) and creatine phosphokinase were elevated from 1.07mg/dL and 7,542U/L to 2.5mg/dL and 96,700U/L on the second day of hospitalization, respectively. T2 fat suppression muscle magnetic resonance imaging showed high-intensity signals in the trunk and thigh muscles. Therefore, he was diagnosed with acute kidney injury due to rhabdomyolysis associated with influenza A infection. Hemodialysis was initiated on the fourth day of hospitalization because of oliguria and increase in serum Cr level to 6.8mg/dL. Hemodialysis was performed 14 times in 28 days and finally withdrawn. On the 50th day of hospitalization, he was discharged. Although rhabdomyolysis is one of the complications associated with influenza infection, it rarely leads to severe acute kidney injury that requires hemodialysis. Here, we report a case of rhabdomyolysis and severe acute kidney injury complicated by influenza A infection.