2021 Volume 12 Issue 1 Pages 64-68
A woman in her 40s ingested a cresol soap solution several hours prior to transportation to the hospital, resulting in emesis, loss of consciousness, respiratory failure and hypotension. Physical examination showed chemical burns due to the cresol to approximately 50% of the head and neck, and blood tests showed a creatinine level of 0.97mg/dL. Continuous hemodialysis (CHD) was started from the first day of admission because of hyperkalemia. We maintained a mean blood pressure of 65mmHg or higher and a proper fluid volume. Oliguria was observed on the 3rd day. CHD was changed to intermittent hemodialysis on the 11th day. After 13 days of oliguria and anuria, the urine volume recovered and hemodialysis was discontinued on the 21st day. The serum creatinine level recovered to 0.76mg/dL 9 months from the time of admission. Cresol poisoning can cause multiple organ failure including acute kidney injury (AKI). In particular, cases of percutaneous absorption can increase the risk of AKI than oral ingestion, because cresol is not metabolized by the first-pass effect in the liver. For cresol poisoning with percutaneous absorption, attention should be paid to the onset of AKI and treatment should be performed with a view to renal prognosis.
