2013 Volume 4 Issue 1 Pages 81-86
We conducted a retrospective study to determine the impact of acute blood purification strategies on patient outcome. Sixty-one critically ill patients who required acute blood purification between January and December 2011 in our institution were included. Data on patient characteristics and disease severity were obtained through medical records and the prognostic factors determined. Severity was evaluated using APACHEⅡscores, the number of organ dysfunctions, the presence of sepsis, and the affected organ. The severity of acute kidney injury (AKI) was evaluated using the RIFLE classification. Patients were divided into a survival or non-survival group, according to whether they survived for more than or less than 90 days, respectively. In the non-survival group, the morbidity of multiple organ dysfunction syndrome and the number of failed organs were significantly higher than in the survival group. Furthermore, in subanalysis of patients with AKI, the continuous renal replacement therapy (CRRT) group, which was initiated with CRRT, had higher APACHEⅡscores and a lower survival rate compared with the intermittent renal replacement therapy (IRRT) group, which was initiated with IRRT. In the multivariate analysis of prognostic factors, the APACHEⅡscore was identified as a meaningful independent factor. Taken together, the findings suggest that the APACHEⅡscore can be used as an independent prognostic factor of patient survival, even in patients who require acute blood purification therapy.
