Journal of Japan Society for Blood Purification in Critical Care
Online ISSN : 2434-219X
Print ISSN : 2185-1085
Clinical effects of different surface areas of PMMA membrane-CHDF therapy with PMX-DHP in sepsis
Hiroaki OnoHidetoshi SaitouMasataka HaraTatsuo KunihiroHidenobu TakahashiNobuyuki Hirohashi
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Keywords: sepsis, PMMA, large-area
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2016 Volume 7 Issue 2 Pages 108-112

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Abstract

Polymethylmethacrylate membrane continuous hemodiafiltration (PMMA-CHDF) therapy was used at our hospital, in conjunction with endotoxin absorption therapy, to treat septic shock due to intra-abdominal infection. The performance characteristics of a hemofilter CH-1.0N® were compared with those of a hemofilter large-area CH-1.8W® before and after the introduction of CH-1.8W® at our hospital in October 2013. A single CH-1.8W® had a significantly longer operational life span; it was associated with a significantly reduced catecholamine dose 12 hours after implementation and significantly increased urine volumes 24 hours after implementation. These results suggest that the large-area hemofilter CH-1.8W® is more suitable for performing PMMA-CHDF in cases of severe sepsis due to an intra-abdominal infection.

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© 2016, Japan Society for Blood Purification in Critical Care
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